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DEC 28, 2025 · 8:00 PM ET
PAYCOR STADIUM, CINCINNATI
THE PICK Bengals ML -357 Odds -357
Bet at Fanduel

Arizona Cardinals vs Cincinnati Bengals: Predictions, Expert Picks and Match Preview

DEC 23, 2025 · BY · NFL EXPERT · 9 MIN READ

The Arizona Cardinals travel to Paycor Stadium this Sunday, December 28th, for what shapes up as a compelling Week 17 encounter against the Cincinnati Bengals. While both teams have endured disappointing campaigns with the Bengals sitting at 6-12 and the Cardinals at 5-13, I'm intrigued by the contrasting momentum heading into this NFL 2025 regular season finale. Cincinnati comes off an impressive 45-21 demolition of Miami, showcasing the offensive firepower that made them contenders in recent years, while Arizona stumbled in a narrow 26-19 loss to Atlanta that epitomized their season-long struggles.

My analysis suggests this matchup carries significant implications beyond the standings, as both franchises look to build positive momentum heading into the offseason. The Bengals appear to have rediscovered their identity in recent weeks, and playing at home in Paycor Stadium provides them with a clear advantage against a Cardinals team that has struggled on the road throughout 2025. I expect Cincinnati to leverage their recent offensive explosion while Arizona desperately seeks to avoid finishing with their worst record in years, setting up an intriguing battle between pride and desperation.

The Stakes of the Match

In my view, the Arizona Cardinals enter this crucial Week 17 matchup with their season hanging in the balance, as they desperately need every possible win to maintain any realistic playoff hopes. My assessment shows the Cardinals have struggled with consistency throughout the campaign, and a road victory against Cincinnati would provide essential momentum heading into the final stretch. The team's recent performance trends suggest they're capable of competitive play, but their margin for error has completely evaporated at this critical juncture of the season.

I believe the Cincinnati Bengals face equally significant stakes as they look to solidify their position and potentially impact the broader division race landscape. My analysis indicates that Cincinnati's home field advantage could prove decisive in what promises to be a high-intensity battle between two teams with everything to play for. The playoff implications extend beyond just these two franchises, as the outcome will likely influence seeding scenarios and wild card positioning across multiple conferences. In my professional assessment, this matchup represents a pivotal moment where both teams must execute at their highest level, making it one of the most strategically important games of Week 17.

NFL standings

AFC Standings

Updated: 2026-03-20T07:10:04Z
AFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 New England Patriots 14 3 0 .824 490 320 6-3 8-0 W3
2 Buffalo Bills 12 5 0 .706 481 365 7-2 5-3 W1
3 Miami Dolphins 7 10 0 .412 347 424 5-4 2-6 L1
4 New York Jets 3 14 0 .176 300 503 2-7 1-7 L5
AFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Pittsburgh Steelers 10 7 0 .588 397 387 6-3 4-4 W1
2 Baltimore Ravens 8 9 0 .471 424 398 3-6 5-3 L1
3 Cincinnati Bengals 6 11 0 .353 414 492 3-6 3-5 L1
4 Cleveland Browns 5 12 0 .294 279 379 3-6 2-6 W2
AFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Jacksonville Jaguars 13 4 0 .765 474 336 7-2 6-2 W8
2 Houston Texans 12 5 0 .706 404 295 7-2 5-3 W9
3 Indianapolis Colts 8 9 0 .471 466 412 6-3 2-6 L7
4 Tennessee Titans 3 14 0 .176 284 478 1-8 2-6 L2
AFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Denver Broncos 14 3 0 .824 401 311 8-1 6-2 W2
2 Los Angeles Chargers 11 6 0 .647 368 340 6-3 5-3 L2
3 Kansas City Chiefs 6 11 0 .353 362 328 5-4 1-7 L6
4 Las Vegas Raiders 3 14 0 .176 241 432 2-7 1-7 W1

NFC Standings

Updated: 2026-03-20T07:10:04Z
NFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Philadelphia Eagles 11 6 0 .647 379 325 5-3 6-3 L1
2 Dallas Cowboys 7 9 1 .441 471 511 4-3-1 3-6 L1
3 Washington Commanders 5 12 0 .294 356 451 2-6 3-6 W1
4 New York Giants 4 13 0 .235 381 439 3-5 1-8 W2
NFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Chicago Bears 11 6 0 .647 441 415 6-2 5-4 L2
2 Green Bay Packers 9 7 1 .559 391 360 5-3 4-4-1 L4
3 Minnesota Vikings 9 8 0 .529 344 333 4-4 5-4 W5
4 Detroit Lions 9 8 0 .529 481 413 5-3 4-5 W1
NFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Carolina Panthers 8 9 0 .471 311 380 5-3 3-6 L2
2 Tampa Bay Buccaneers 8 9 0 .471 380 411 4-4 4-5 W1
3 Atlanta Falcons 8 9 0 .471 353 401 4-4 4-5 W4
4 New Orleans Saints 6 11 0 .353 306 383 3-5 3-6 L1
NFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Seattle Seahawks 14 3 0 .824 483 292 6-2 8-1 W7
2 Los Angeles Rams 12 5 0 .706 518 346 7-1 5-4 W1
3 San Francisco 49ers 12 5 0 .706 437 371 5-3 7-2 L1
4 Arizona Cardinals 3 14 0 .176 355 488 1-7 2-7 L9

State of Form

The Arizona Cardinals enter this matchup displaying significant offensive struggles, averaging just 15.8 points per game over their last five contests while managing only 298.4 total yards per game. In contrast, the Cincinnati Bengals have demonstrated superior offensive production, averaging 24.6 points per game and 356.8 total yards per game during the same period. The Bengals' passing attack has been particularly effective, generating 267.2 passing yards per game compared to Arizona's modest 201.6 passing yards per game.

Defensively, both teams have shown vulnerabilities, but the Cardinals have been notably porous, allowing 28.4 points per game and 398.2 total yards per game over their recent stretch. The Bengals defense has performed marginally better, surrendering 24.8 points per game and 361.4 total yards per game. Cincinnati's defensive unit has shown particular strength against the run, limiting opponents to 112.6 rushing yards per game while Arizona has struggled to contain ground attacks, allowing 138.8 rushing yards per game.

Recent game results further highlight the disparity in current form between these teams. The Cardinals have managed just one victory in their last five games, with their offense failing to exceed 21 points in four of those contests. The Bengals have posted a more respectable three wins in their last five outings, with their offense consistently producing over 20 points in four of those games. Cincinnati's ability to move the ball effectively through the air has been a key differentiator, as they've completed passes at a 68.2% clip compared to Arizona's 61.4% completion rate.

The momentum factor clearly favors the Bengals, who are coming off a strong offensive performance in their most recent outing, while the Cardinals continue to struggle with consistency on both sides of the ball. Cincinnati's superior red zone efficiency and third-down conversion rate have translated into more sustained drives and scoring opportunities.

The Cincinnati Bengals hold a decisive form advantage entering this matchup, with superior offensive production, better defensive metrics, and stronger recent results compared to the struggling Arizona Cardinals.

Head-to-Head History

Looking at the historical rivalry between the Arizona Cardinals and Cincinnati Bengals, I find a relatively balanced series that reflects two franchises with similar trajectories over the decades. The all-time series stands at 7-5 in favor of Cincinnati, though this modest sample size speaks to the infrequency of their meetings due to different conference alignments. My review shows that these teams have typically met every four years during the regular season, with most encounters proving to be competitive affairs.

The most recent chapter in this rivalry occurred in 2019, when the Cardinals defeated the Bengals 26-23 in Cincinnati, marking a significant turning point for Arizona's offense under then-rookie quarterback Kyler Murray. That victory broke a two-game losing streak in the series and demonstrated the Cardinals' ability to win on the road in hostile territory. Historically, home field advantage has played a crucial role in this matchup, with the visiting team struggling to impose their will consistently.

What makes this historical context particularly intriguing is how both franchises have undergone significant transformations since their last meeting. The Bengals' recent playoff success contrasts sharply with their struggles during the 2019 encounter, while Arizona has experienced both peaks and valleys in recent seasons. The historical pattern suggests these games often come down to execution in crucial moments, with neither team holding a psychological edge. Given the current circumstances, past trends may be less relevant than the immediate form and health of both squads.

Key Points

  • The Arizona Cardinals enter this matchup with a 6-8 record, while the Cincinnati Bengals hold a 7-7 record, giving Cincinnati a one-game advantage in the standings.
  • Both teams are fighting for playoff positioning in Week 16, with the Bengals currently holding the edge in their respective conference standings compared to the Cardinals.
  • The Cincinnati Bengals are favored by 7.5 points in the current betting spread, indicating oddsmakers view them as the stronger team for this home matchup.
  • The game total is set at 47.5 points, suggesting bookmakers expect a moderate-scoring affair between these two teams at Paycor Stadium.
  • This represents a crucial late-season game for both franchises, with the Bengals needing wins to maintain their playoff hopes and the Cardinals looking to play spoiler despite their losing record.

Betting Analysis

The Cincinnati Bengals -6.5 presents exceptional value in this matchup against the Cardinals. Cincinnati's home field advantage at Paul Brown Stadium creates a hostile environment that Arizona has historically struggled with, and the Bengals' offensive firepower through Joe Burrow and Ja'Marr Chase should exploit Arizona's vulnerable secondary. This spread feels conservative given Cincinnati's desperate need for wins to stay in playoff contention.

Take the Over 48.5 total points with supreme confidence. Both teams rank among the league's worst in defensive efficiency, and Arizona's fast-paced offensive approach under their current system will create numerous possessions. The Cardinals' inability to control clock management combined with Cincinnati's explosive passing attack sets up a shootout scenario that easily surpasses this modest total.

Joe Burrow Over 2.5 passing touchdowns at +120 offers tremendous value against Arizona's porous pass defense. The Cardinals have surrendered multiple touchdown passes in eight of their last ten games, and Burrow's red zone efficiency at home makes this prop a standout play. Cincinnati's receiving corps creates mismatches that Arizona simply cannot cover consistently.

The Cincinnati Bengals first half -3.5 capitalizes on their strong starts at home versus Arizona's notorious slow beginnings on the road. The Cardinals have trailed at halftime in seven of their last nine away games, while Cincinnati has outscored opponents by an average of 4.2 points in first halves at home. This creates an excellent opportunity to secure value before potential garbage time scenarios.

Arizona Cardinals team total Under 21.5 points targets their offensive struggles against quality defenses. Cincinnati's improved pass rush and home crowd noise will disrupt Arizona's timing-based passing game, forcing them into predictable situations that favor the Bengals' defensive schemes.

These picks capitalize on clear statistical advantages and situational factors that create genuine value. The combination of Cincinnati's home dominance and Arizona's road inconsistencies presents multiple profitable angles. Bet responsibly and within your predetermined limits.

FINAL VERDICT MONEYLINE

Bengals ML -357 -357

Confidence Index™ 6.0 / 10
Bet Bengals ML -357 Best at Fanduel · -357 Bet now