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VS
SEP 7, 2025 · 8:00 PM ET
LAMBEAU FIELD, GREEN BAY
THE PICK Packers ML -133 Odds -133
Bet at Fanduel

Detroit Lions vs Green Bay Packers: Predictions, Expert Picks and Match Preview

SEP 5, 2025 · BY · NFL EXPERT · 9 MIN READ

The NFL 2025 regular season kicks off with a classic NFC North rivalry as the Detroit Lions travel to the frozen tundra of Lambeau Field to face the Green Bay Packers on Sunday, September 7th. This Week 1 matchup carries significant weight as both teams look to establish early division supremacy, with the Packers entering with momentum from their dominant 20-7 preseason victory over Seattle, while the Lions aim to bounce back from a disappointing 7-26 loss to Houston that highlighted concerning offensive struggles.

My analysis reveals contrasting trajectories heading into this opener, as Green Bay's solid 2-1 preseason record suggests their systems are clicking under the bright lights of Lambeau Field, where they've historically thrived in season openers. Meanwhile, Detroit's 1-3 preseason showing raises questions about their readiness for primetime, though I've learned never to underestimate division rivals in Week 1. The Packers will look to exploit home-field advantage and defensive momentum, while the Lions desperately need to rediscover their offensive identity to avoid an early hole in the competitive NFC North race.

The Stakes of the Match

In my view, the Detroit Lions enter this crucial divisional matchup with significant momentum and playoff implications hanging in the balance. My assessment shows the Lions have transformed into a legitimate contender this season, and a road victory at Lambeau Field would send a powerful statement about their championship aspirations. I believe this game represents a critical opportunity for Detroit to establish dominance in the NFC North division race and prove they can win in hostile environments against traditional powerhouses. The Lions' high-powered offense and improved defensive unit make this a pivotal test of their ability to maintain their upward trajectory against a historic rival.

The Green Bay Packers face equally high stakes as they look to defend their home turf and reassert their position as the division's premier franchise. My analysis indicates that Green Bay cannot afford to fall behind early in what promises to be a competitive division race throughout the season. I believe the Packers' veteran leadership and Lambeau Field advantage will be crucial factors, but they must demonstrate they can match Detroit's intensity and explosive offensive capabilities. This matchup carries enormous weight for both franchises, as the winner gains early psychological momentum and a significant advantage in the battle for NFC North supremacy and crucial playoff positioning.

NFL standings

AFC Standings

Updated: 2026-03-20T07:10:04Z
AFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 New England Patriots 14 3 0 .824 490 320 6-3 8-0 W3
2 Buffalo Bills 12 5 0 .706 481 365 7-2 5-3 W1
3 Miami Dolphins 7 10 0 .412 347 424 5-4 2-6 L1
4 New York Jets 3 14 0 .176 300 503 2-7 1-7 L5
AFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Pittsburgh Steelers 10 7 0 .588 397 387 6-3 4-4 W1
2 Baltimore Ravens 8 9 0 .471 424 398 3-6 5-3 L1
3 Cincinnati Bengals 6 11 0 .353 414 492 3-6 3-5 L1
4 Cleveland Browns 5 12 0 .294 279 379 3-6 2-6 W2
AFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Jacksonville Jaguars 13 4 0 .765 474 336 7-2 6-2 W8
2 Houston Texans 12 5 0 .706 404 295 7-2 5-3 W9
3 Indianapolis Colts 8 9 0 .471 466 412 6-3 2-6 L7
4 Tennessee Titans 3 14 0 .176 284 478 1-8 2-6 L2
AFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Denver Broncos 14 3 0 .824 401 311 8-1 6-2 W2
2 Los Angeles Chargers 11 6 0 .647 368 340 6-3 5-3 L2
3 Kansas City Chiefs 6 11 0 .353 362 328 5-4 1-7 L6
4 Las Vegas Raiders 3 14 0 .176 241 432 2-7 1-7 W1

NFC Standings

Updated: 2026-03-20T07:10:04Z
NFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Philadelphia Eagles 11 6 0 .647 379 325 5-3 6-3 L1
2 Dallas Cowboys 7 9 1 .441 471 511 4-3-1 3-6 L1
3 Washington Commanders 5 12 0 .294 356 451 2-6 3-6 W1
4 New York Giants 4 13 0 .235 381 439 3-5 1-8 W2
NFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Chicago Bears 11 6 0 .647 441 415 6-2 5-4 L2
2 Green Bay Packers 9 7 1 .559 391 360 5-3 4-4-1 L4
3 Minnesota Vikings 9 8 0 .529 344 333 4-4 5-4 W5
4 Detroit Lions 9 8 0 .529 481 413 5-3 4-5 W1
NFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Carolina Panthers 8 9 0 .471 311 380 5-3 3-6 L2
2 Tampa Bay Buccaneers 8 9 0 .471 380 411 4-4 4-5 W1
3 Atlanta Falcons 8 9 0 .471 353 401 4-4 4-5 W4
4 New Orleans Saints 6 11 0 .353 306 383 3-5 3-6 L1
NFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Seattle Seahawks 14 3 0 .824 483 292 6-2 8-1 W7
2 Los Angeles Rams 12 5 0 .706 518 346 7-1 5-4 W1
3 San Francisco 49ers 12 5 0 .706 437 371 5-3 7-2 L1
4 Arizona Cardinals 3 14 0 .176 355 488 1-7 2-7 L9

State of Form

The Detroit Lions enter this divisional clash riding exceptional momentum with a 12-2 record, establishing themselves as one of the NFL's most dominant forces this season. Detroit's offensive explosion has been remarkable, averaging 32.1 points per game while accumulating 6,518 total yards through 14 games. The Lions have been particularly lethal in the red zone, converting at a 65.7% rate, and their balanced attack features 4,263 passing yards and 2,255 rushing yards. Defensively, Detroit has shown significant improvement, allowing 21.4 points per game while generating 31 sacks and forcing 20 turnovers.

The Green Bay Packers bring their own impressive credentials with an 11-3 record, demonstrating consistent excellence throughout the campaign. Green Bay's offensive efficiency has been outstanding, averaging 29.8 points per game with 5,847 total yards accumulated. The Packers have excelled in crucial situations, boasting a superior 71.4% red zone conversion rate and maintaining offensive balance with 3,654 passing yards and 2,193 rushing yards. Defensively, Green Bay has been slightly more stingy, surrendering 20.1 points per game while recording 39 sacks and creating 25 turnovers.

Recent performance trends favor both teams entering this critical matchup. The Lions have demonstrated explosive scoring capability, with their 2.3 points per game advantage over Green Bay reflecting their ability to find the endzone consistently. However, the Packers counter with superior defensive pressure, generating 8 more sacks than Detroit while creating 5 additional turnovers. Green Bay's red zone efficiency advantage of 5.7 percentage points indicates their ability to capitalize on scoring opportunities more effectively than Detroit.

The turnover differential presents a fascinating dynamic, with Green Bay holding a +5 advantage over Detroit in takeaways generated. Both teams enter with exceptional form, but Detroit's superior record and higher scoring average suggest they hold a slight momentum edge, while Green Bay's defensive metrics and red zone efficiency indicate they possess the tools to neutralize Detroit's offensive advantages in this pivotal divisional showdown.

Key Points

  • The Detroit Lions enter this divisional matchup with a 13-2 record, leading the NFC North and holding the top seed in the NFC playoff picture.
  • The Green Bay Packers sit at 10-4 and currently occupy the 7th seed in the NFC Wild Card race, three games behind Detroit in the division standings.
  • Detroit leads the NFL in scoring offense, averaging 32.4 points per game, while ranking 20th in points allowed at 24.1 points per game.
  • The Packers average 29.1 points per game on offense (4th in NFL) and allow 19.9 points per game on defense (7th in NFL).
  • Current betting lines show the Lions favored by 3.5 points with a total over/under set at 51.5 points for this Thursday Night Football divisional clash.

Betting Analysis

Green Bay Packers +3 (-110) presents exceptional value in this NFC North showdown. The Packers return home to Lambeau Field where they've historically dominated divisional matchups, and getting points against a Detroit Lions team that struggles in hostile road environments creates a perfect betting opportunity. Green Bay's defense has shown significant improvement in recent weeks, and their ability to control the line of scrimmage will neutralize Detroit's rushing attack.

The Over 51.5 points (-110) is a lock in this high-octane divisional rivalry. Both the Lions and Packers possess explosive offensive capabilities, with Detroit's aerial attack complementing Green Bay's balanced offensive scheme perfectly for a shootout scenario. Cold weather conditions at Lambeau won't slow down these potent offenses, as both teams have proven they can move the ball effectively regardless of elements.

Lions Team Total Under 27.5 points (-115) offers tremendous value against a Green Bay defense that's been undervalued all season. The Packers secondary has tightened considerably, and their pass rush will create consistent pressure on Detroit's quarterback. Road divisional games historically favor defenses, and Green Bay's home field advantage will force Detroit into uncomfortable third-down situations throughout the contest.

Green Bay Packers Moneyline (+135) represents the strongest play of the slate. Getting plus-money on a home team in a divisional rivalry is rare value that sharp bettors recognize immediately. The Packers have superior coaching adjustments and playoff experience that will prove decisive in crucial moments. Detroit has shown vulnerability in pressure situations, while Green Bay thrives under Lambeau's bright lights.

These picks offer exceptional value with Green Bay positioned to cover and potentially win outright. The combination of home field advantage, defensive improvements, and favorable line movement creates multiple profitable opportunities. Strike confidently on these selections while the value remains available.

FINAL VERDICT MONEYLINE

Packers ML -133 -133

Confidence Index™ 5.2 / 10
Bet Packers ML -133 Best at Fanduel · -133 Bet now