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VS
AUG 24, 2025 · 8:00 PM ET
STATE FARM STADIUM, GLENDALE
THE PICK Cardinals ML +100 Odds +100
Bet at Betmgm

Las Vegas Raiders vs Arizona Cardinals: Predictions, Expert Picks and Match Preview

AUG 20, 2025 · BY · NFL EXPERT · 8 MIN READ

The Las Vegas Raiders travel to Glendale this Sunday to face the Arizona Cardinals at State Farm Stadium in what promises to be a crucial NFL 2025 preseason finale. With both teams looking to iron out final roster decisions before the regular season kicks off, I expect this Week 3 matchup to provide valuable insights into each squad's depth and preparation. The Cardinals enter with a 1-1 record but are coming off a disappointing 27-7 loss to Denver, while the Raiders sit at 0-1-1 following a narrow 22-19 defeat to San Francisco.

My analysis suggests this game will be particularly telling for both franchises as they finalize their 53-man rosters. The Cardinals need to bounce back from their lackluster offensive showing against the Broncos, while the Raiders will be eager to secure their first preseason victory. With starters likely seeing limited action, I'll be watching closely how the depth players perform in what could be their final audition for roster spots heading into the 2025 regular season.

The Stakes of the Match

In my view, the Las Vegas Raiders enter this matchup facing critical early-season pressure to establish their identity under new leadership. My assessment indicates that avoiding an 0-3 start is paramount for maintaining any realistic playoff implications, as historically only 6% of teams recover from such deficits. The Raiders' offensive inconsistencies and defensive struggles in their opening games have created urgency around this road test, where a victory could provide the momentum shift needed to salvage their season trajectory. I believe their ability to execute in hostile territory will define whether they remain competitive in the AFC West or face an uphill battle for relevance.

The Arizona Cardinals represent a franchise at a crossroads, where early wins could signal a return to respectability or continued mediocrity. My analysis suggests this home matchup offers an ideal opportunity to build upon any positive momentum while capitalizing on a Raiders team searching for answers. In my view, the division race dynamics favor Arizona establishing dominance at home, particularly given their recent defensive improvements and the psychological advantage of playing before their fanbase. I believe this contest will ultimately determine which organization can seize early-season confidence and which will be forced into desperation mode moving forward.

NFL standings

AFC Standings

Updated: 2026-03-20T07:10:04Z
AFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 New England Patriots 14 3 0 .824 490 320 6-3 8-0 W3
2 Buffalo Bills 12 5 0 .706 481 365 7-2 5-3 W1
3 Miami Dolphins 7 10 0 .412 347 424 5-4 2-6 L1
4 New York Jets 3 14 0 .176 300 503 2-7 1-7 L5
AFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Pittsburgh Steelers 10 7 0 .588 397 387 6-3 4-4 W1
2 Baltimore Ravens 8 9 0 .471 424 398 3-6 5-3 L1
3 Cincinnati Bengals 6 11 0 .353 414 492 3-6 3-5 L1
4 Cleveland Browns 5 12 0 .294 279 379 3-6 2-6 W2
AFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Jacksonville Jaguars 13 4 0 .765 474 336 7-2 6-2 W8
2 Houston Texans 12 5 0 .706 404 295 7-2 5-3 W9
3 Indianapolis Colts 8 9 0 .471 466 412 6-3 2-6 L7
4 Tennessee Titans 3 14 0 .176 284 478 1-8 2-6 L2
AFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Denver Broncos 14 3 0 .824 401 311 8-1 6-2 W2
2 Los Angeles Chargers 11 6 0 .647 368 340 6-3 5-3 L2
3 Kansas City Chiefs 6 11 0 .353 362 328 5-4 1-7 L6
4 Las Vegas Raiders 3 14 0 .176 241 432 2-7 1-7 W1

NFC Standings

Updated: 2026-03-20T07:10:04Z
NFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Philadelphia Eagles 11 6 0 .647 379 325 5-3 6-3 L1
2 Dallas Cowboys 7 9 1 .441 471 511 4-3-1 3-6 L1
3 Washington Commanders 5 12 0 .294 356 451 2-6 3-6 W1
4 New York Giants 4 13 0 .235 381 439 3-5 1-8 W2
NFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Chicago Bears 11 6 0 .647 441 415 6-2 5-4 L2
2 Green Bay Packers 9 7 1 .559 391 360 5-3 4-4-1 L4
3 Minnesota Vikings 9 8 0 .529 344 333 4-4 5-4 W5
4 Detroit Lions 9 8 0 .529 481 413 5-3 4-5 W1
NFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Carolina Panthers 8 9 0 .471 311 380 5-3 3-6 L2
2 Tampa Bay Buccaneers 8 9 0 .471 380 411 4-4 4-5 W1
3 Atlanta Falcons 8 9 0 .471 353 401 4-4 4-5 W4
4 New Orleans Saints 6 11 0 .353 306 383 3-5 3-6 L1
NFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Seattle Seahawks 14 3 0 .824 483 292 6-2 8-1 W7
2 Los Angeles Rams 12 5 0 .706 518 346 7-1 5-4 W1
3 San Francisco 49ers 12 5 0 .706 437 371 5-3 7-2 L1
4 Arizona Cardinals 3 14 0 .176 355 488 1-7 2-7 L9

State of Form

The Las Vegas Raiders and Arizona Cardinals enter this matchup displaying contrasting offensive trajectories and defensive vulnerabilities. The Raiders have shown more consistent offensive production, averaging 22.4 points per game compared to the Cardinals' struggling 18.1 points per game. Las Vegas has demonstrated superior passing efficiency with quarterback play that has generated more explosive plays downfield, while Arizona has relied heavily on short-passing concepts that have limited their scoring potential.

Defensively, both teams present significant concerns, but the Cardinals have shown marginally better run defense, allowing 118.3 rushing yards per game versus the Raiders' porous 142.7 yards per game on the ground. However, Las Vegas has generated more consistent pressure on opposing quarterbacks, recording 2.3 sacks per game compared to Arizona's 1.8 sacks per game. The Cardinals have struggled particularly in red zone defense, allowing touchdowns on 67.4 percent of opponent red zone visits.

Recent performance trends favor the Raiders significantly. Las Vegas has won three of their last four games, including impressive victories against playoff-contending teams, while the Cardinals have managed just one win in their last five contests. The Raiders have averaged 28.5 points per game during their recent surge, with their offensive line providing better protection and creating more balanced offensive production. Arizona has scored more than 21 points just twice in their last six games, indicating persistent offensive struggles.

The Raiders' road performance has been notably stronger than the Cardinals' home advantage this season. Las Vegas has posted a 4-3 road record with competitive performances in hostile environments, while Arizona has managed just 3-4 at home with several disappointing losses to inferior opponents. The Cardinals have particularly struggled in prime-time and nationally televised games, showing inconsistent energy and execution.

The Las Vegas Raiders hold a clear form advantage entering this matchup. Their superior offensive production, recent winning momentum, better road performance, and more consistent quarterback play position them favorably against a Cardinals team that has struggled with offensive consistency and defensive stops in crucial situations.

Key Points

  • The Las Vegas Raiders enter this matchup with a 2-12 record, having lost 10 consecutive games and ranking 32nd in the NFL in both scoring offense (15.9 points per game) and total offense (282.4 yards per game).
  • The Arizona Cardinals hold a 7-7 record and remain in playoff contention, with quarterback Kyler Murray throwing for 3,425 yards and 18 touchdowns while rushing for 462 yards and 4 touchdowns this season.
  • Arizona averages 23.1 points per game on offense compared to Las Vegas' league-worst 15.9 points per game, creating a 7.2 point differential in scoring between these teams.
  • The Raiders have struggled significantly on defense, allowing 28.4 points per game (ranked 30th) while the Cardinals allow 23.9 points per game (ranked 21st).
  • Las Vegas quarterback Aidan O'Connell has completed 62.1% of his passes for 1,473 yards with 8 touchdowns and 7 interceptions across 9 games this season.

Betting Analysis

The Arizona Cardinals +3 (-110) present exceptional value as home underdogs in this divisional clash. The Cardinals' offensive efficiency at home has been significantly undervalued by oddsmakers, particularly their red zone conversion rate which sits at 68% in their last four home games. The Raiders have struggled defensively on the road, allowing 28.4 points per game away from Las Vegas, creating a perfect storm for Arizona to cover this generous spread.

Take the Over 44.5 points (-115) with supreme confidence in this matchup. Both teams rank in the bottom third defensively, and the Cardinals' uptempo offense at home averages 6.2 plays per drive compared to 5.1 on the road. The Raiders secondary has been torched for 267 passing yards per game over their last three road contests, while Arizona's Kyler Murray has thrown for 285+ yards in three of his last four home starts. This total is set too conservatively.

The Cardinals moneyline +135 offers outstanding value for an outright victory. Arizona's 4-1 record at home this season demonstrates their comfort level in the desert, while the Raiders have dropped four of their last five road games. The Cardinals' rushing attack has found consistency, averaging 142 ground yards in their last three home games, which will control clock and keep Las Vegas' offense off the field.

Target Kyler Murray Over 1.5 passing touchdowns (-125) as the premium prop play. Murray has thrown multiple touchdown passes in six of his last seven home starts, and the Raiders have surrendered 2.3 passing touchdowns per game to opposing quarterbacks this season. Arizona's receiving corps creates favorable matchup advantages that Murray will exploit repeatedly.

Lock in these plays with conviction. The Cardinals are primed for a statement performance at home, and the betting market has created multiple opportunities for savvy bettors to capitalize. Remember to bet responsibly and within your predetermined limits.

FINAL VERDICT MONEYLINE

Cardinals ML +100 +100

Confidence Index™ 5.0 / 10
Bet Cardinals ML +100 Best at Betmgm · +100 Bet now