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DEC 7, 2025 · 8:00 PM ET
STATE FARM STADIUM, GLENDALE
THE PICK Rams ML -500 Odds -500
Bet at Fanduel

Los Angeles Rams vs Arizona Cardinals: Predictions, Expert Picks and Match Preview

DEC 6, 2025 · BY · NFL EXPERT · 10 MIN READ

The Los Angeles Rams travel to State Farm Stadium in Glendale this Sunday, December 7th, for a crucial Week 14 divisional clash against the Arizona Cardinals. With an impressive 11-4 record, I see the Rams fighting to maintain their playoff positioning despite a disappointing 28-31 loss to Carolina in their last outing. Meanwhile, the Cardinals sit at 5-10 following their narrow 17-20 defeat to Tampa Bay, making this essentially a pride game for Arizona as their postseason hopes have all but evaporated.

From my analysis, this NFL 2025 regular season matchup presents contrasting narratives - the Rams need to bounce back and secure their playoff seeding, while the Cardinals are playing spoiler in what's been a disappointing campaign. Both teams are coming off losses, which adds an interesting dynamic to this NFC West battle. I expect the Rams to be highly motivated to get back on track, but division games at State Farm Stadium are never straightforward, and Arizona will be desperate to finish their season on a positive note.

The Stakes of the Match

In my view, the Los Angeles Rams enter this Week 14 clash facing a critical juncture in their season, where every game carries significant playoff implications. My assessment shows the Rams desperately need momentum to salvage what has been an inconsistent campaign, as they battle to stay relevant in the competitive NFC landscape. A victory in Arizona would provide essential breathing room and keep their postseason aspirations alive, while a loss could effectively derail their championship defense hopes. The Rams' point differential and recent performance trends suggest they're capable of explosive games but lack the consistency needed for a deep playoff run.

I believe the Arizona Cardinals face equally high stakes as they look to build on any positive momentum in what has been a rebuilding season. The Cardinals' home field advantage becomes crucial in this division race context, as they seek to play spoiler while evaluating their young core for future seasons. My analysis indicates this matchup represents a pivotal moment for both franchises - the Rams fighting to extend their championship window, while Arizona aims to establish an identity moving forward. The timing in Week 14 makes this encounter particularly significant, as both teams understand that strong finishes can dramatically alter offseason narratives and organizational confidence heading into 2024.

NFL standings

AFC Standings

Updated: 2026-03-20T07:10:04Z
AFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 New England Patriots 14 3 0 .824 490 320 6-3 8-0 W3
2 Buffalo Bills 12 5 0 .706 481 365 7-2 5-3 W1
3 Miami Dolphins 7 10 0 .412 347 424 5-4 2-6 L1
4 New York Jets 3 14 0 .176 300 503 2-7 1-7 L5
AFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Pittsburgh Steelers 10 7 0 .588 397 387 6-3 4-4 W1
2 Baltimore Ravens 8 9 0 .471 424 398 3-6 5-3 L1
3 Cincinnati Bengals 6 11 0 .353 414 492 3-6 3-5 L1
4 Cleveland Browns 5 12 0 .294 279 379 3-6 2-6 W2
AFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Jacksonville Jaguars 13 4 0 .765 474 336 7-2 6-2 W8
2 Houston Texans 12 5 0 .706 404 295 7-2 5-3 W9
3 Indianapolis Colts 8 9 0 .471 466 412 6-3 2-6 L7
4 Tennessee Titans 3 14 0 .176 284 478 1-8 2-6 L2
AFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Denver Broncos 14 3 0 .824 401 311 8-1 6-2 W2
2 Los Angeles Chargers 11 6 0 .647 368 340 6-3 5-3 L2
3 Kansas City Chiefs 6 11 0 .353 362 328 5-4 1-7 L6
4 Las Vegas Raiders 3 14 0 .176 241 432 2-7 1-7 W1

NFC Standings

Updated: 2026-03-20T07:10:04Z
NFC East
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Philadelphia Eagles 11 6 0 .647 379 325 5-3 6-3 L1
2 Dallas Cowboys 7 9 1 .441 471 511 4-3-1 3-6 L1
3 Washington Commanders 5 12 0 .294 356 451 2-6 3-6 W1
4 New York Giants 4 13 0 .235 381 439 3-5 1-8 W2
NFC North
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Chicago Bears 11 6 0 .647 441 415 6-2 5-4 L2
2 Green Bay Packers 9 7 1 .559 391 360 5-3 4-4-1 L4
3 Minnesota Vikings 9 8 0 .529 344 333 4-4 5-4 W5
4 Detroit Lions 9 8 0 .529 481 413 5-3 4-5 W1
NFC South
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Carolina Panthers 8 9 0 .471 311 380 5-3 3-6 L2
2 Tampa Bay Buccaneers 8 9 0 .471 380 411 4-4 4-5 W1
3 Atlanta Falcons 8 9 0 .471 353 401 4-4 4-5 W4
4 New Orleans Saints 6 11 0 .353 306 383 3-5 3-6 L1
NFC West
RK TEAM W L T PCT PF PA HOME AWAY STRK
1 Seattle Seahawks 14 3 0 .824 483 292 6-2 8-1 W7
2 Los Angeles Rams 12 5 0 .706 518 346 7-1 5-4 W1
3 San Francisco 49ers 12 5 0 .706 437 371 5-3 7-2 L1
4 Arizona Cardinals 3 14 0 .176 355 488 1-7 2-7 L9

State of Form

The Los Angeles Rams enter this matchup displaying inconsistent offensive production, averaging 21.8 points per game while struggling with turnover issues that have plagued their recent performances. Their passing attack has shown flashes of brilliance but lacks the consistency needed for sustained drives, particularly in road environments where they've managed just 1.2 touchdowns per game over their last five contests. The Arizona Cardinals counter with a more balanced offensive approach, posting 24.3 points per game while demonstrating superior red zone efficiency at 67% compared to the Rams' 58% conversion rate.

Defensively, the Cardinals have established clear superiority, allowing just 19.1 points per game while generating 2.4 takeaways per contest over their recent stretch. Their pass defense has been particularly stout, limiting opposing quarterbacks to a 84.2 passer rating and recording 12 interceptions in their last six games. The Rams defense has struggled significantly, surrendering 28.7 points per game and failing to generate consistent pressure with only 1.8 sacks per game. Their run defense has been especially vulnerable, allowing 142.3 rushing yards per game and 4.9 yards per carry.

Recent momentum strongly favors Arizona, as they've won four of their last six games while covering the spread in five of those contests. Their home field advantage has been pronounced, outscoring opponents by an average of 11.4 points at State Farm Stadium. The Rams have managed just two victories in their last six outings, with both wins coming against teams with losing records. Their road struggles are evident in a 2-5 away record, where they've been outscored by 8.2 points per game.

Contextually, the Cardinals have demonstrated superior situational football, converting 44% of third downs compared to the Rams' 36% efficiency. Arizona's time of possession advantage of 32:18 per game reflects their ability to control game flow and limit opponent opportunities.

The Arizona Cardinals hold a decisive form advantage entering this matchup, demonstrating superior performance across offensive efficiency, defensive consistency, recent results, and home field execution compared to the struggling Los Angeles Rams.

Head-to-Head History

Looking at the historical rivalry between the Los Angeles Rams and Arizona Cardinals, I find a fascinating dynamic that has evolved significantly over the decades. The Rams have traditionally held the upper hand in this NFC West divisional matchup, with their overall series lead reflecting periods of dominance dating back to when both franchises called different cities home. The rivalry intensified dramatically when the Rams returned to Los Angeles in 2016, creating renewed energy in their twice-yearly meetings.

My review of recent trends shows the Cardinals have been more competitive in this matchup over the past several seasons, particularly during their playoff runs. The venue factor has played a crucial role historically, with State Farm Stadium in Arizona proving to be a challenging environment for visiting teams. The Cardinals have shown they can exploit the Rams' aggressive defensive schemes when playing at home, while the Rams have typically relied on their offensive firepower to control games in Arizona.

The most significant pattern I've observed is how these teams' contrasting styles create unpredictable outcomes. When both teams are healthy and competitive, these games often come down to turnover battles and special teams execution. The Rams' Super Bowl championship run in 2021 marked a turning point in recent meetings, but Arizona has consistently shown they can match Los Angeles' intensity. Historical trends suggest this rivalry produces close, hard-fought games regardless of each team's record, making past performance a valuable but not definitive predictor for their upcoming clash.

Key Points

  • The Los Angeles Rams enter this matchup with a 9-6 record while the Arizona Cardinals hold an 8-7 record, with the Rams having won one more game this season.
  • Both teams are coming off recent victories, with the Rams defeating the New York Jets 19-9 and the Cardinals beating the Carolina Panthers 36-30 in overtime in their previous games.
  • The Cardinals have shown strong offensive production recently, scoring 36 points against Carolina, while the Rams managed 19 points in a defensive battle against New York.
  • This NFC West divisional matchup features two teams separated by just one game in the standings, making it crucial for playoff positioning in the final weeks.
  • The Rams currently hold the head-to-head advantage in wins this season at 9-6 compared to Arizona's 8-7 record, positioning them slightly better in the divisional race.

Betting Analysis

The Arizona Cardinals +3.5 (-110) present exceptional value in this divisional matchup. The Cardinals have covered the spread in four of their last six home games, while the Los Angeles Rams have struggled on the road, failing to cover in three consecutive away contests. Arizona's home field advantage at State Farm Stadium creates a hostile environment that consistently disrupts opposing offenses, making this spread too generous for a divisional rivalry game.

Target the Over 47.5 points (-115) with supreme confidence. Both teams rank in the bottom half of NFL defenses in yards allowed per game, and their previous meeting this season produced 52 total points. The Rams offense has found rhythm in recent weeks, averaging 28 points over their last four games, while the Cardinals have exceeded 24 points in five of their last seven contests. Weather conditions favor offensive production with clear skies and minimal wind expected.

Kyler Murray Over 245.5 passing yards (-120) offers tremendous upside potential. Murray has surpassed this total in six of his last eight starts, and the Rams secondary has surrendered 267 passing yards per game over their last five outings. With key weapons healthy and Arizona likely playing from behind or in competitive situations, Murray's arm will be featured prominently throughout this contest.

The Cardinals moneyline +155 represents the day's premium value play. Division games consistently produce unexpected outcomes, and Arizona has won two of their last three meetings against Los Angeles. The Cardinals desperation factor cannot be understated as they fight for playoff positioning, while the Rams have shown inconsistency in crucial road spots this season.

These selections offer exceptional value based on current form, historical matchup data, and situational advantages. The Cardinals spread and total points over provide the strongest foundation for success. Remember to bet responsibly and within your predetermined limits.

FINAL VERDICT MONEYLINE

Rams ML -500 -500

Confidence Index™ 6.2 / 10
Bet Rams ML -500 Best at Fanduel · -500 Bet now